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. 2011 Mar;27(3):106–110. doi: 10.1016/j.pt.2010.12.004

Figure 3.

Figure 3

The Plasmodium LCCL protein family (schematic). The names given are the most commonly used for these proteins in P. berghei (Pb) and P. falciparum (Pf). All proteins possess a predicted amino-terminal endoplasmic reticulum signal peptide (red). Various domains are shown with significant homologies to known protein domains. See Pfam/Smart entries (in brackets) for further detailed information on these domains. Black: domain related to Limulus coagulation factor C, Coch-5b2 and Lgl1 (LCCL) domain (Pfam03815, Smart00603); light green: domain related to polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain (Pfam01477, Smart00308); light-blue: domain related to scavenger receptor cysteine-rich (SRCR) domain (Pfam00530, Smart00202); pink: domain related to pentaxin/laminin-G domain (Pfam00354, Smart00159); orange: domain related to ricin-type beta trefoil lectin domain (Pfam00161, Smart00458); red: domain related to coagulation factor 5/8 carboxy-terminal domain/discoidin domain (Pfam00754, Smart00231); yellow: domain related to fibrillar collagen (COLFI) carboxy-terminal domain (Pfam01410, Smart00038), also known as neurexin and collagen-related (NEC) domain; dark-blue: Levanase-like domain; purple: domain related to anthrax protective antigen domain (Pfam07691); dark green: domain related to fibronectin type-II domain (Pfam00040, Smart00059); grey: domains related to apicomplexan-specific cysteine-rich domain. This diagram was compiled from [12–15].