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. Author manuscript; available in PMC: 2011 Jul 12.
Published in final edited form as: Dev Cell. 2010 Jun 15;18(6):1022–1029. doi: 10.1016/j.devcel.2010.05.015

Figure 2. Nkx6 proteins suppress acinar cell differentiation.

Figure 2

(A,H) Schematic of the Pdx1-Nkx6.1 and Pdx1-Nkx6.2 transgenes. Immunofluorescence staining of pancreata from Pdx1-Nkx6.1 embryos at e12.5 and e14.5 (B-G) and Pdx1-Nkx6.2 embryos at e14.5 (I-N) shows that ectopic expression of Nkx6.1 or Nkx6.2 blocks expression of Ptf1a and amylase.