Table 4.
Mosaik/Artemis alignment analysis identifies conserved genes encoding candidate vaccine antigens.
| Conserved in A. marginale | Identification method | A. centrale ortholog | Conserved between A. marginale/centrale | |
|---|---|---|---|---|
| omp1(AM1139) | Yes | Outer membrane protein | ACIS_00234 | No |
| omp4(AM1164) | Yes | Outer membrane protein | ACIS_00227 | No |
| omp6(AM1219)a | Yes | Outer membrane protein | None | No |
| omp11(AM1255) | Yes | Outer membrane protein | ACIS_00140 | No |
| omp12(AM1257) | Yes | Outer membrane protein | ACIS_00139 | No |
| opag1(AM1143)a | Yes | Outer membrane protein | ACIS_00231 | No |
| opag2(AM1142) | Yes | Outer membrane protein | ACIS_00232 | No |
| opag3(AM1140) | Yes | Outer membrane protein | ACIS_00233 | No |
| msp4(AM090) | Yes | Outer membrane protein | ACIS_01187 | No |
| AM779 | Yes | Surface X-linking | ACIS_00557 | No |
| AM780 | Yes | Surface X-linking | ACIS_00556 | No |
| pal(AM854) | Yes | Surface X-linking | ACIS_00486 | No |
| purD(AM1011) | Yes | Surface X-linking | ACIS_00340 | No |
| virB3(AM815) | Yes | Type 4 secretion | ACIS_00521 | No |
| virB4-1(AM814) | Yes | Type 4 secretion | ACIS_00522 | No |
| virB4-2(AM1053) | Yes | Type 4 secretion | ACIS_00304 | No |
| virB6(AM811) | Yes | Type 4 secretion | ACIS_00526 | No |
| virB8-1(AM1316) | Yes | Type 4 secretion | ACIS_00090 | No |
| virB9-2(AM1315) | Yes | Type 4 secretion | ACIS_00091 | No |
| virB10(AM1314) | Yes | Type 4 secretion | ACIS_00092 | No |
| virB11(AM1313) | Yes | Type 4 secretion | ACIS_00093 | No |
aNot expressed.