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. 2011 Jul;54(4):e451–e454. doi: 10.1016/j.ejmg.2011.04.009

Table 1.

Methylation-values at IC1 and IC2 in the family.

Individual IC1
IC2
CTS1 CTS6
II-2 7.1 4.3 1
II-3 1 1 1
III-1 10.2 3.4 1
III-2 1 1 1
NCa 1 ± 0.36 1 ± 0.21 1 ± 0.19

Numbers represent me/unme ratios at ICs, as determined by COBRA. The ratios were normalised against the average values of 50 control samples. Numbers greater than 1 indicate gain of methylation.

a

NC, normal controls.