Table 1.
Controls (n = 42) |
Amnestic MCI Pts (n= 29) |
P value | |
---|---|---|---|
Age - mean (SD) | 64.83 (8.34) | 70.31 (7.00) | .005 |
Years of Education - mean (SD) | 15.00 (2.27) | 14.00 (2.84) | .105 |
Gender: Female / Male | 31 / 11 | 19 / 10 | .452 |
Race: White / Black | 34 / 8 | 22 / 7 | .606 |
DRS Total Score (max = 144) - mean (SD) | 139.38 (2.94) | 131.14 (4.71) | .001 |
MMSE (max = 30) - mean (SD) | 29.43 (1.04) | 28.00 (1.44) | .001 |
CDR Staging: 0.0 / 0.5 | 42 / 0 | 0 / 29 | .001 |
Cholinesterase Inhibitor Use: yes/ no | ---- | 11 / 18 | ---- |
CCTI Standard 1: Expressing Choice (range: 0–4)* | 3.76 (0.48) | 3.86 (0.35) | .612 |
CCTI Standard 3: Appreciating Consequences (range: 0–8) * | 7.50 (1.11) | 6.93 (1.39) | .116 |
CCTI Standard 4: Reasoning about Treatment (range: 0–12) * | 10.93 (4.55) | 8.14 (4.09) | .027 |
CCTI Standard 5: Understanding Treatment (range: 0–78)* | 63.90 (9.12) | 46.93 (12.93) | .001 |
NAA/Cr * | 1.34 (0.12) | 1.31 (0.14) | .432 |
Cho/Cr * | 0.64 (0.05) | 0.67 (0.06) | .035 |
mI/Cr * | 0.90 (0.10) | 0.98 (0.11) | .006 |
values adjusted for age