Table 3.
Neuropsychological Test Performance of Study Groups
| Controls (n = 42) |
Amnestic MCI Pts (n= 29) |
P value* | |
|---|---|---|---|
| DRS Attention | 36.26 (1.01) | 34.83 (1.83) | .001 |
| Spatial Span Total (WMS-III) | 14.67 (3.24) | 12.55 (2.82) | .037 |
| Boston Naming Test (30-item) | 27.64 (1.89) | 24.28 (4.81) | .001 |
| Semantic Word Fluency | 59.24 (9.93) | 47.10 (6.93) | .001 |
| DRS Memory | 24.02 (1.00) | 20.79 (3.75) | .001 |
| Logical Memory I (WMS-R) | 26.90 (4.49) | 17.00 (7.45) | .001 |
| Logical Memory II (WMS-R) | 23.55 (4.87) | 10.62 (7.29) | .001 |
| Visual Reproduction I (WMS-III) | 77.57 (12.24) | 58.59 (15.79) | .001 |
| Visual Reproduction II (WMS-III) | 54.48 (18.37) | 26.86 (17.38) | .001 |
| CVLT-II Total Learning Trials 1–5 | 47.95 (7.94) | 31.69 (7.25) | .001 |
| CVLT-II Short Delay Free Recall | 9.52 (2.73) | 4.31 (2.42) | .001 |
| CVLT-II Long Delay Free Recall | 10.93 (2.65) | 4.62 (2.91) | .001 |
| DRS Construction | 5.74 (0.7) | 5.62 (0.8) | .419 |
| CLOX 2 | 13.52 (1.09) | 13.07 (1. 07) | .321 |
| DRS Conceptualization | 36.55 (2.29) | 34.28 (3.55) | .012 |
| DRS Initiation/Perseveration | 36.71 (0.60) | 35.38 (2.13) | .002 |
| Trail Making Test A (sec.) | 30.48 (9.89) | 42.93 (21.26) | .007 |
| Trail Making Test B (sec.) | 74.19 (19.63) | 141.41 (71.04) | .001 |
| CLOX 1 | 11.86 (1.78) | 11.10 (2.13) | .143 |
| Digit Symbol (WAIS-III) | 65.71 (14.65) | 44.71 (11.04) | .001 |
*
corrected for age
CLOX = Executive Clock Drawing Test; CVLT-II = California Verbal Learning Test II; DRS = Dementia Rating Scale; WAIS-III = Wechsler Adult Intelligence Scale III; WMS-III = Wechsler Memory Scale III; WMS-R = Wechsler Memory Scale - Revised