Table 4.

Case-Control Analyses: SNP-Based Results

Sample	Cases/Control Subjects	Ethnicity	Case Frequency (G Allele)a	Control Frequency (G Allele)	p-Valueb	Odds Ratio (Allele)c	95% CI
SNP1
1	151/127	Caucasian	.551	.556	.92
4	711/708	Caucasian	.579	.583	.886
10d	612/704	Caucasian	.602	.573	.132
11	299/645	Caucasian	.589	.552	.12
12d	255/242	Caucasian	.541	.59	.122
13d	580/596	Caucasian	.567	.611	.033	1.26(A)	1.644–.965
5	271/576	Brazilian	.576	.568	.747
8d	609/157	Chinese	.6	.544	.095
SNP4
1	151/127	Caucasian	.487	.469	.676
4	711/708	Caucasian	.486	.532	.021	1.2(T)	1.388–1.037
10d	612/704	Caucasian	.508	.496	.518
11	299/645	Caucasian	.52	.487	.178
12d	255/242	Caucasian	.477	.474	.938
13d	580/596	Caucasian	.491	.528	.075
5	271/576	Brazilian	.416	.408	.75
8d	609/157	Chinese	.526	.631	.002	1.544(T)	2.022–1.179
SNP7
1	151/127	Caucasian	.557	.551	.89
4	711/708	Caucasian	.579	.606	.145
10d	612/704	Caucasian	.602	.573	.132
11	299/645	Caucasian	.594	.554	.105
12d	255/242	Caucasian	.5	.53	.392
13d	580/596	Caucasian	.561	.615	.006	1.254(A)	1.482–1.061
5	271/576	Brazilian	.576	.569	.777
8d	609/157	Chinese	.603	.553	.121
SNP18
1	151/127	Caucasian	.514	.504	.819
4	711/708	Caucasian	.51	.549	.042	1.171(A)	1.363–1.007
10d	612/704	Caucasian	.534	.525	.644
11	299/645	Caucasian	.548	.509	.128
12d	255/242	Caucasian	.498	.502	.891
13d	580/596	Caucasian	.516	.56	.03	1.194(A)	1.407–1.014
5	271/576	Brazilian	.445	.424	.381
8d	609/157	Chinese	.509	.466	.19

Results for the SNP-based analyses from individual samples.

Samples are grouped by ethnicity.

SNP, single nucleotide polymorphism; CI, confidence interval.

^aFrequencies are given with reference to the G allele at each SNP.

^bp-values are trends test results from genotype data.

^cOdds ratio, associated allele, and 95% confidence intervals (CI) for significant associations.

^dUnpublished samples.