Table 5.
Case-Control Analyses: Four SNP Haplotype Results by Sample
Sample | Ethnicity | Cases/Control Subjects |
G-G-G-G Frequency (Case) |
G-G-G-G Frequency (Control) |
A-T-A-A Frequency (Case) |
A-T-A-A Frequency (Control) |
Omnibus p-Valuea |
---|---|---|---|---|---|---|---|
1 | Caucasian | 151/127 | .486 | .484 | .416 | .408 | .596 |
4 | Caucasian | 711/708 | .459 | .497 | .37 | .343 | .445 |
10b | Caucasian | 612/704 | .505 | .491 | .372 | .395 | .566 |
11 | Caucasian | 299/645 | .521 | .502 | .368 | .402 | .64 |
12b | Caucasian | 255/242 | .478 | .463 | .438 | .378 | .037 |
13b | Caucasian | 580/596 | .477 | .525 | .408 | .359 | .032 |
5 | Brazilian | 271/576 | .412 | .402 | .399 | .416 | .739 |
8b | Chinese | 609/157 | .481 | .284 | .376 | .234 | .0001 |
Estimated haplotype frequencies in cases and control subjects from individual samples.
Samples are grouped by ethnicity.
SNP, single nucleotide polymorphism.
p-values represent EM algorithm estimations of SNP haplotypes omnibus likelihood ratio tests of association for all haplotypes.
Unpublished samples.