TABLE I.
FISH Characterization of the 6p25 Deletion in the Patient
| Location on 6p | Distance from 6p telomere (Mb) | Clones 6p Tel (FISH probes) | Markers and genes | Current case report |
|---|---|---|---|---|
| 25.3 | 0.5 | DJ20B11 | FLJ11026 | − |
| 25.3 | 1.5 | DJ118b18 | FOXC1 | − |
| 25.3 | 1.7 | DJ 279I9 | GMDS | − |
| 25.3 | 2.1 | DJ33B19 | GMDS | − |
| 25 | B24 | P1 REGION | − | |
| 25 | DJ36I2 | PX TO CDYL | − | |
| 25 | 5.1 | DJ67E13 | ALO35653 | − |
| 25 | 5.75 | DJ182O16 | D6S1685 | − |
| 25 | 6.1 | DJ103H18 | D6S1677 | − |
| 25 | 6.4 | DJ287K15 | D6S477(F13A) | − |
| 25 | 6.4 | DJ23021 | D6S1677 | − |
| 25 | 6.5 | DJ80N2 | PRP1 | − |
| 25.1 | 6.7 | DJ470L22 | AL136361 | − |
| 25 | 7.3 | DJ69L16 | D6S1159 | − |
| 25 | 7.5 | DJ29L9 | DSP | − |
| 25 | 7.3 | DJ69L16 | D6S1159 | + |
| 25/24.3 | 7.3 | DJ155I9 | D6S1640 | + |
| 25/24.3 | 8 | DJ303A1 | BMP6 | + |
| 24.3 | 8.9 | DJ133H11 | D6S410 | + |
| 24.3 | DJ136F24 | WI-6424 | + | |
| 24.3 | DJ860I9 | + | ||
| 24.3 | 11.2 | DJ110P13 | SGC33794 | + |
| 24.3 | DJ151C13 | STSG26237 | + |
–, absence of signals on deletion chromosome 6 for that probe; +, signals detected on both intact and deletion chromosomes 6 for that probe.