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. 2011 Jun 14;16(6):066009. doi: 10.1117/1.3589348

Figure 5.

Figure 5

Fluorescence tomography images obtained from (a) ICG injected mouse of tumor size 3 mm×4 mm and (b) 2-nitroimidazole-ICG injected mouse of tumor size 6 mm×5 mm. The color bars are the fluorophore concentration in micromolars. (a) For ICG; before, during and post-injection images. (b) For 2-nitroimidazole-ICG; before, during and post-injection images. (c) and (d) Fluorescence images acquired from Li-COR scanner of the ICG injected mouse and 2-nitroimidazole-ICG injected mouse. (e) and (f) Corresponding H& E stains. (g) and (h) 40×H&E of the marked region in (e) and (f), respectively. (i) and (j) Corresponding immuno-histochemistry stains (brown) for tumor hypoxia.