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pH dependence of the GAG effect on fibril formation
Fibril formation is shown by the increase in ThT fluorescence (normalized) versus time in hours. Heparan sulfate was present at a concentration of 0.1mg/mL. a) AL-09 fibril nucleation in the presence of heparan sulfate, pH 3–7. b) AL-103 fibril nucleation in the presence of heparan sulfate, pH 3–7.
