Table 1.

Ultrasensitive quantification of HBV precore G1896A and G1899A mutations from 20 HBeAg-positive patient samples.

No.	TVL*	G1896A*	G1899A*	G1896A%	G1899A%
1	4.52E+08	-	8.20E+03	-	0.002
2	2.29E+09	2.08E+06	5.21E+05	0.091	0.023
3	3.17E+08	6.29E+06	3.31E+05	1.986	0.105
4	8.81E+08	1.30E+07	2.30E+06	1.479	0.261
5	1.13E+09	3.23E+04	-	0.003	-
6	2.00E+09	4.45E+06	-	0.222	-
7	1.53E+09	8.17E+07	9.08E+06	5.326	0.592
8	8.67E+07	1.63E+05	7.00E+04	0.188	0.081
9	4.42E+09	1.36E+07	9.06E+06	0.308	0.205
10	7.18E+08	2.68E+06	1.15E+06	0.373	0.160
11	1.90E+08	6.83E+05	1.71E+05	0.360	0.090
12	8.13E+07	5.13E+05	-	0.631	-
13	1.81E+09	1.01E+07	2.52E+06	0.560	0.140
14	4.78E+07	6.09E+05	2.61E+05	1.273	0.546
15	5.73E+08	3.15E+06	3.50E+05	0.550	0.061
16	1.23E+09	1.36E+06	7.15E+04	0.110	0.006
17	2.97E+06	2.31E+01	-	0.001	-
18	1.29E+09	2.09E+06	5.23E+05	0.162	0.040
19	5.72E+06	4.08E+03	1.02E+03	0.071	0.018
20	6.32E+08	1.38E+06	7.27E+04	0.219	0.012

^*TVL (total viral load), G1896A and G1899A are in copies/ml. G1896A is the “total” G1896A mutation (G1896A + G1896A/G1899A). Likewise, G1899A is the total G1899A whether or not associated with G1896A. For example, a mixture of 10% G1896A and 20% G1896A/G1899A indicates 30% G1896A and 20% G1899A.