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Wortmannin inhibits the cell migration induced by IL-8. (A) After 20 min pretreatment with 100 mM wortmannin, EA.Hy926 cells were subjected to a migration assay in the absence or presence of 100 ng/ml IL-8. The cell migration was increased along with the stimulated time. (B) The changes of the cell migration distance in different groups with the duration. IL-8 group. *P<0.05 vs. other groups; ##P<0.01 vs. IL-8 group. Scale bar=600 μm. Three independent experiments were conducted.
