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. 2011 Jun 21;7(6):782–791. doi: 10.7150/ijbs.7.782

FIG 6.

FIG 6

Wortmannin inhibits the upregulation of Rac1 and RhoA induced by IL-8. After 20 min pretreatment with 100 mM wortmannin, the level of total RhoA in EA.Hy926 cells was determined by Western blotting (A). *P<0.05 vs. control group; and the level of total Rac1 in EA.Hy926 cells was determined by Western blotting (B). **P<0.01 vs. control group. After 20 min pretreatment with 100 mM wortmannin and stimulated by IL-8 for the indicated time, the level of total RhoA in EA.Hy926 cells was determined by Western blotting (C) # P<0.05; ## P<0.01; and the level of total Rac1 in EA.Hy926 cells was determined by Western blotting (D) # P<0.05; ## P<0.01.