Table 1.

Comparative behavioral and physiological analysis of wildtype and CK−−/−− mice.

	Wildtype	CK−−/−−
Body weight (g)	35.1±0.7	25.4±0.8***
Food intake per day
Absolute (g per animal)	5.3±0.1	4.4±0.2***
Relative (mg per animal/g bw)	151±4.9	175±6.2**
Activity (counts)
Day
06:00–09:00	409±45	613±158
09:00–12:00	250±34	365±81
12:00–15:00	242±53	392±57
15:00–18:00	247±47	280±65
Total day	1148±104	1649±263
Night
18:00–21:00	570±192	475±61
21:00–00:00	593±99	1042±262
00:00–03:00	515±105	854±189
03:00–06:00	469±92	638±142
Total night	2247±425	3009±570
Blood parameters
Glucose (mmol/l)	10.2±0.3	8.7±0.4**
Leptin (ng/ml)	1.3±0.1	0.9±0.1*
FFA (mmol/l)	0.47±0.04	0.36±0.04
TG (mmol/l)	0.60±0.08	0.37±0.04*

All values are expressed as means±SEM. bw, body weight; FFA, free fatty acids; TG, triglycerides. Number of animals n=9–11 per group. Significantly different from wildtype (Student’s t-test):

^*P<0.05;

^**P<0.01;

^***P<0.001.