Table 2.
Symptoms, signs and orphan status in HIV positive and negative subjects
| HIV Status | ||||||||
|---|---|---|---|---|---|---|---|---|
| Infected (n = 60) |
Uninfected (n = 540) |
Total N = 600 |
OR (95% CI) | P | ||||
| No. | % | No. | % | No. | % | |||
| Symptom | ||||||||
| Fever | 45 | 75.0 | 310 | 57.4 | 355 | 59.2 | 2.23(1.21,4.10) | 0.008 |
| Cough | 39 | 65.0 | 128 | 23.7 | 167 | 27.8 | 5.98(3.39,10.53) | 0.000 |
| Fast breathing | 8 | 1.3 | 82 | 15.2 | 90 | 15.0 | 0.86(0.39,1.88) | 0.849 |
| Diarrhoea | 24 | 40.0 | 57 | 10.6 | 81 | 13.5 | 5.65(3.15,10.14) | 0.000 |
| Weight loss/falter | 25 | 41.7 | 63 | 11.7 | 88 | 14.7 | 5.41(3.04,9.62) | 0.000 |
| Seizures | 2 | 3.3 | 106 | 19.6 | 108 | 18.0 | 0.14(0.03,0.59) | 0.001 |
| Coma | - | - | 21 | 3.9 | 21 | 3.5 | - | 0.254 |
| Chronic diarrhoea | 7 | 11.7 | 1 | 1.9 | 8 | 1.3 | 71.19(8.60,589.65) | 0.000 |
| Recurrent otorrohea | 11 | 18.3 | 11 | 2.0 | 22 | 3.7 | 10.80(4.45,26.17) | 0.000 |
| Signs | ||||||||
| Pallor | 20 | 33.3 | 150 | 27.8 | 170 | 28.3 | 1.30 (0.74,2.30) | 0.368 |
| Jaundice | 2 | 3.3 | 74 | 13.7 | 76 | 12.7 | 0.22 (0.05,0.91) | 0.022 |
| Oral thrush | 8 | 13.3 | 8 | 1.5 | 16 | 2.7 | 10.23 (3.69,28.4) | 0.000 |
| Lymphadenopathy | 33 | 55.0 | 33 | 6.1 | 66 | 11.0 | 18.78 (10.12,34.86) | 0.000 |
| Parotid fullness | 13 | 21.7 | 3 | 0.6 | 16 | 2.7 | 49.51(13.63,179.92) | 0.000 |
| Otorrhoea | 7 | 11.7 | 6 | 1.1 | 13 | 2.2 | 11.76 (3.81,36.26) | 0.000 |
| Skin lesions | 24 | 40.0 | 32 | 5.9 | 56 | 9.3 | 10.58 (5.65,19.83) | 0.000 |
| Hepatomegaly | 43 | 71.7 | 236 | 43.7 | 279 | 46.5 | 3.26 (1.81,5.86) | 0.000 |
| Splenomegaly | 19 | 31.7 | 66 | 12.2 | 85 | 14.2 | 3.33 (1.82,6.08) | 0.000 |
Persistent fever: Unexplained fever (intermittent or constant) lasting ≥ 1 month, Chronic diarrhoea: At least two loose stools per day for ≥ 30 days, Recurrent otorrhoea: ≥ 2 episodes of ear discharge from the same ear