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. 2011 Jul 1;25(13):1412–1425. doi: 10.1101/gad.2018911

Figure 2.

Figure 2.

Suppression of PTPN23, PTPRG, and PTPRR induced distinct stimulatory effects on mammary epithelial cell motility. The motility of MCF10A/ERBB2 cells that expressed the indicated PTP shRNA was measured in the absence (A) or presence (B) of AP1510, the activator of ERBB2. For each condition, the number of migrating cells was counted in 21 random fields. The mean number of migrating cells in the shLuc control was 5.6 cells per field in the absence (A) and 18.2 cells per field in the presence (B) of AP1510. In each case, the number of migrating cells in the shLuc control was normalized to 1. Error bars represent SEM (n = 3); (*) P < 0.05; (**) P < 0.01.