Table 1.

Patient characteristics of study sample (N = 2, 513).

	N (%)
Line of therapy
First-line	2004 (80%)
Second-line	509 (20%)
Age
Mean (SD)	69.7
Median (range)	70.7 (30–92)
Gender
Male	1378 (55%)
Female	1135 (45%)
Stage at diagnosis
I-IIIA	538 (24%)
IIIB-IV	1664 (76%)
Missing	311
Performance status
0	1045 (46%)
1	1032 (46%)
2+	175 (8%)
Missing	261
Comorbidity status
Any comorbidity (1+ comorbidities)	553 (22%)
Specific comorbidities
Moderate/severe renal disease	37 (1.5%)
Congestive heart failure	106 (4.2%)
Chronic obstructive pulmonary disorder	218 (9%)
Cerebrovascular disease	33 (1.3%)
Diabetes	162 (6.4%)
Peripheral vascular disease	113 (4.5%)
Myocardial infarction	21 (0.8%)
Liver disease	16 (0.6%)