Fig 4. Deletion of the ZF significantly impairs NEMO polyubiquitination but has a minimal effect on MAPK activities in PMA/ionomycin stimulated T-cells.
(A) Western blot analysis of MAPK activities in EDI E391X T-cells after PMA/ionomycin treatment. (B) Polyubiquitination of NEMO in T-cells from E391X patient after PMA/ionomycin stimulation.