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Young’s modulus (A), water content (B) and calcium content (C) of the implanted HA hydrogel constructs containing TGF-β3-loaded microspheres (MS+T) after 28 or 56 days of subcutaneous implantation in nude mice, *p<0.05 vs. Day 28 (n=4)). Von Kossa staining of the implanted HA constructs (MS+T), bar = 500 μm (D).
