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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Dev Neurobiol. 2011 Aug;71(8):680–689. doi: 10.1002/dneu.20882

Table 1.

Summary of transcription factor expression in the dentate gyrus.

Transcription
Factor
Expression
Pattern
Type of Study and Stage
of Development
References

Pax6 Type-1 and type-2a
cells
Expression (postnatal and
adult)
Loss of function (postnatal)
Maekawa et al., 2005
Nacher et al., 2005
Hodge et al., 2008
Roybon et al., 2009
Tbr2 Type-2b and type-3
cells
Expression (adult)
Loss of function
(embryonic conditional null
mutant)
Arnold et al., 2008
Hodge et al., 2008
Roybon et al., 2009
Tbr1 Immature neurons
and mature
neurons
Expression (adult) Hodge et al., 2008
Roybon et al., 2009
Sox2 Type-1 and type-2a
cells
Expression (adult)
Loss of Function
(embryonic null mutant)
Loss of function (adult
inducible conditional
knockout)
Eriksson, 2004
Ferri et al., 2004
Komitova and
Suh et al., 2007
Favaro et al., 2009
Kuwabara et al., 2009
Ehm et al., 2010
Lugert et al., 2010
Sox3 Type-3 cells and
immature neurons
Expression (adult) Wang et al., 2006
Sox11 Type-3 cells and
immature neurons
Expression (adult)
Gain of function (in vitro
overexpression)
Haslinger et al.,
2011
Hes5 Type-1 cells Expression (adult) Lugert et al., 2010
Ascl1 Type-1 and type-2a
cells
Expression (adult)
Lineage tracing (adult)
Gain of function (retroviral
overexpression in vivo)
Kim et al., 2007
Hodge et al., 2008
Roybon et al., 2009
Neurog2 Type-2a and type-
2b cells
Expression (postnatal,
adult)
Loss of function (postnatal)
Gain of function (postnatal
retroviral overexpression)
Ozen et al., 2007
Hodge et al., 2008
Roybon et al., 2009
NeuroD1 Type-2b, type-3,
and immature
neurons
Expression (postnatal,
adult)
Loss of function
(embryonic null mutant)
Loss of function (adult
conditional knockout)
Lee et al., 2000
Liu et al., 2000
Schwab et al., 2000
Seki, 2002
Del Turco et al., 2004
Seri et al., 2004
Hodge et al., 2008
Gao et al., 2009
Kuwabara et al., 2009
Roybon et al., 2009
NPAS3 Not determined Loss of function
(embryonic null mutant)
Pieper et al., 2005
FoxG1 Type-2 and type-3
cells
Loss of function (postnatal) Shen et al., 2006
Eagleson et al., 2007
Prox1 Type-3 cells,
immature and
mature neurons
Expression (postnatal,
adult)
Loss of function (postnatal
and adult conditional
knockout)
Lavado and Oliver, 2007
Lavado et al., 2010
CREB Immature neurons Expression (adult)
Loss of function (adult)
Gain of function (adult)
Nakagawa et al., 2002a, b
Fujioka et al., 2004
Jagasia et al., 2009
HHS Vulnerability Disclosure