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In spite of a similar norepinephrine-induced vasoconstriction of the aortic rings from normal (NL) and hypothyroid (HTX) rats, adenosine- (ADO-) induced vasodilation is markedly higher in the HTX aortic rings. Increased number of adenosine receptors or a higher sensitivity to the receptors to exogenous adenosine may explain the higher sensitivity of HTX aortic rings to ADO.
