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. 2011 Mar 24;2:45–56. doi: 10.2147/RRTM.S13679

Figure 3.

Figure 3

Titer of anti-VAL-1 IgG and anti-ALT-2 IgG antibodies in the sera of immunized mice after 4 immunizations at 2-week intervals. IgG levels were measured using an ELISA. DNA – DNA vaccinated group, Protein – Protein vaccinated group, Prime boost – DNA Prime protein boost vaccinated group, and Control – vector plus alum controls. A) Sera collected from mice immunized with monovalent BmVAL-1 vaccine. B) Sera collected from mice immunized with monovalent BmALT-2 vaccine. C) Sera collected from mice immunized with BmVAL-1/BmALT-2 multivalent vaccine. Dotted lines: values for anti-BmVAL-1 IgG; solid lines: values for anti-BmALT-2 IgG; N = 10. Data represent results from one of two experiments with comparable results.