Table 1.

Percent larval death (protection) in mice challenged with 20 B. malayi L3

Vaccination groups	Mean ± SD live L3s	Percent protection
pVAXBmVAL-1 DNA monovalent homologous	12.2 ± 4.5	39.0% ± 1.7%**
rBmVAL-1 protein monovalent homologous	10.4 ± 3.1	48.0% ± 2.1%*
pVAXBmVAL-1 DNA plus rBmVAL-1 monovalent heterologous	9.2 ± 2.2	54.0% ± 3.1%*
pVAXBmALT-2 DNA monovalent homologous	9.8 ± 2.1	51.0% ± 2.5%*
rBmALT-2 protein monovalent homologous	7.0 ± 1.1	65.0% ± 4.2%*
pVAXBmALT-2 DNA plus rBmALT-2 monovalent heterologous	5.1 ± 0.5	74.5% ± 3.1%*
pVAXBmVAL-1/ALT-2 DNA multivalent homologous	8.6 ± 0.1	57.0% ± 2.2%*
rBmVAL-1/rBmALT-2 protein multivalent homologous	5.2 ± 1.1	74.0% ± 3.3%*
pVAXBmVAL-1/BmALT-2 DNA plus rBmVAL-1/rBmALT-2 multivalent heterologous	4.4 ± 0.4	82.0% ± 2.2%*
pVAX + alum control	20 ± 0	0%

Notes: Significance

^*P < 0.01

^**P < 0.05 compared with control.