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. Author manuscript; available in PMC: 2011 Aug 4.
Published in final edited form as: J Mol Biol. 2010 Dec 9;405(5):1139–1153. doi: 10.1016/j.jmb.2010.11.034

Fig. 2.

Fig. 2

Electron density maps for selected ligands. Regions of the 2Fo-Fc maps (light blue) are shown for bound RNA in (a) the NS3-rU8Br4 structure (2.0Å) and (b) the NS3rU8Br4/ADP•BeF3 structure (2.3Å). Fo-Fc density calculated prior to adding bromine to U4 nucleotide residues in both models is contoured at 4σ and shown in red. (c) A 2Fo-Fc density map (light blue) for ADP•BeF3 bound to NS3 (2.05Å) is superimposed on the final model of the nucleotide, magnesium ion, and two coordinating water molecules.