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. Author manuscript; available in PMC: 2011 Jul 12.
Published in final edited form as: Nat Neurosci. 2009 Feb 22;12(3):311–317. doi: 10.1038/nn.2275

Figure 5. Altered morphology of wild-type neurons cultured with ACM from MeCP2-null astrocytes is evident at the single cell level.

Figure 5

(a) Co-immunostaining in low-density neuronal cultures (6 DIV) with MAP2 (red) and MeCP2 (green) demonstrating aberrant process morphology when cultured in ACM from mutant astrocytes (compare top panels, WT ACM to lower panels Mut ACM). Calibration bar, 30 μm. (b) GFP-expressing neurons show aberrant processes when cultured in mutant ACM (compare top panels, WT ACM to lower panels Mut ACM). Calibration bars, 20 μm.