Table 3.
Serum LDL cholesterol levels in habitual alcohol consumption groups by Mt5178 C/A genotype
| Alcohol consumption | P for trend | |||
|---|---|---|---|---|
| Non- or ex-drinkers | Occasional drinkers | Daily drinkers | ||
| Mt5178C | N = 44 | N = 84 | N = 111 | |
| LDL cholesterol | 135.0 ± 5.2 | 120.5 ± 3.7 | 117.1 ± 3.3* | 0.007 |
| LDL cholesterol † | 135.8 ± 5.2 | 120.4 ± 3.8 | 116.9 ± 3.3** | 0.005 |
| LDL cholesterol ‡ | 135.6 ± 6.3 | 119.5 ± 4.9* | 116.4 ± 4.1** | 0.006 |
| Mt5178A | N = 21 | N = 60 | N = 74 | |
| LDL cholesterol | 121.4 ± 6.7 | 118.5 ± 4.0 | 116.5 ± 3.6 | 0.506 |
| LDL cholesterol † | 122.1 ± 6.7 | 118.4 ± 3.9 | 116.3 ± 3.5 | 0.445 |
| LDL cholesterol ‡ | 121.4 ± 7.5 | 117.6 ± 5.1 | 116.1 ± 4.7 | 0.502 |
LDL: low-density lipoprotein. †LDL cholesterol levels are given as least-square means ± S.E. adjusted for age and body mass index; ‡LDL cholesterol levels are given as least-square means ± S.E. adjusted for age, body mass index, habitual smoking, coffee consumption and antihypertensive medication use. Bonferroni correction for multiple comparisons was applied. *P < 0.05 vs. Non- or ex-drinkers with Mt5178C; **P < 0.01 vs. Non- or ex-drinkers with Mt5178C.