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. Author manuscript; available in PMC: 2011 Jul 12.
Published in final edited form as: Crit Rev Immunol. 2006;26(4):317–352. doi: 10.1615/critrevimmunol.v26.i4.30

Table II.

Mycobacterial antigens recognized by murine CD8+ T cells

Antigena Rv numberb Restrictionc Epitoped Sequencee Frequencyf Tissueg Ref
CFP10 Rv3874 H-2 Kk CFP1032–39 VESTAGSL 1/3i lung (126)
TB10.3 Rv0288 H-2 Kd TB10.320–28 GYAGTLQSL 1/3i lung (122;126)
TB10.4 Rv3019c TB10.420–28
Mtb32 Rv0125 H-2 Db 32C93–102 GAPINSATAM 1/13i lung (158;159)
MPT51 Rv3803c H-2 Dd MPT5124–32 GGPHAVYLL 1/91j spleen (149)
PstS3 Rv0928 H-2 Db PstS3285–293 SGVGNDLVL 1/5650h spleen (203)
MPT64 Rv1980c H-2 Db MPT64190–198 FAVTNDGVI 1/6250i,k spleen (157)
Ag85A Rv3804c H-2 Kd Ag85A144–152 VYAGAMSGL ND (122)
38 kD Rv0934 H-2b 38225–234 ALGENGNGGM ND (106;111;157)
a

Common name for antigen.

b

The Rv designation for the mycobacterial protein.

c

The restricting MHC protein, if known; if not, the H-2 haplotype of the mouse strain.

d

The location of the epitope within protein sequence.

e

The amino acid sequence of the epitope.

f

The frequency of antigen-specific T cells among CD8+ T cells.

g

The tissue used to determine the T cell frequency.

h

Determined using an Elispot assay

i

Determined by flow cytometric analysis using peptide-loaded class I MHC-tetramers.

j

Determined by flow cytometric analysis using intracellular cytokine staining

k

Mice infected with BCG ND, not done