Table 3. Biomarker analysis of TSP50 in CRC.
Variables | Sensitivity | Specificity | PPV | NPV | Youden index | AUC (95% CI) |
Normal and adenoma vs.CRC | 68.4% | 92.5% | 95.6% | 55.2% | 62.0% | 0.812 (0.741–0.883) |
TSP50, testes-specific protease 50; CRC, colorectal carcinoma; PPV, positive predictive values; NPV, negative predictive values; Youden index was calculated as the maximum (sensitivity + specificity - 1); AUC, area under the curve; CI, confidence interval.