Table 4. Backward stepwise multivariate regression analysis of prognostic factors.

Prognostic variables	Indicator of poor prognosis	HR (95% CI)	P-Value
TSP50 expression: Low vs. high	High expression	2.205 (1.214–4.004)	0.009
CEA expression: Low vs. high	High expression	1.813 (1.062–3.096)	0.029
Tumor stage:
I vs II	II	1.988 (0.796–4.961)	0.141
I vs III	III	3.430 (1.380–8.526)	0.008
I vs IV	IV	18.781 (6.316–55.846)	<0.0001

Age, depth of invasion, lymph node metastasis, tumor size and tumor grade were excluded from the model because of P>0.05.

TSP50, testes-specific protease 50; CRC, colorectal carcinoma; CEA, carcinoembryonic antigen; HR, hazard ratio; CI, confidence interval.