Table 2.

Enriched GO pathway analysis for the 291 targeted genes of 16 eQTLs associated with both cisplatin 5 μM induced apoptosis and cytotoxicity.

Category	Enrichment	Count	P-Value	* FDR
GOTERM_BP_FAT	positive regulation of cell proliferation	19	2.3E-05	0.02
GOTERM_BP_FAT	response to estrogen stimulus	10	1.7E-05	0.03
GOTERM_BP_FAT	immune response	24	1.1E-04	0.04
GOTERM_BP_FAT	positive regulation of B cell activation	6	9.2E-05	0.04
GOTERM_BP_FAT	response to steroid hormone stimulus	12	8.9E-05	0.05
GOTERM_BP_FAT	positive regulation of immune response	10	2.1E-04	0.06
GOTERM_BP_FAT	positive regulation of apoptosis	12	4.2E-02	0.52

Note:

^*FDR were calculated using Benjamini–Hochberg– Yekutieli procedure. BP is one of the three categories of GO, meaning biological process.