Table 1.
Patient Demographics and Disease Characteristics Stratified by pCRa Status and Study Group
| Demographic or disease characteristic | pCR (n=25) |
Non-pCR (n=70) |
p value |
|---|---|---|---|
| Age, yearsb | 54.4 (10.57) | 57.24 (12.53) | 0.278 |
| Gender | 0.815 | ||
| Male | 13 (25%) | 40 (75%) | |
| Female | 12 (29%) | 30 (71%) | |
| Histological grade | 0.662 | ||
| Well differentiated | 3 (18%) | 14 (82%) | |
| Moderately differentiated | 22 (33%) | 54 (66%) | |
| Poorly differentiated | 0 (0%) | 2 (100%) | |
| Clinical stage | 0.101 | ||
| II | 3 (13%) | 21 (87%) | |
| III | 22 (31%) | 49 (69%) | |
| Study group (SG)c | 0.161 | ||
| SG1 (n=43) | 8 (19%) | 35 (81%) | |
| SG2 (n=52) | 17 (33%) | 35 (67%) | |
a
Pathologic complete response.
b
Mean is presented with the standard deviation shown in parentheses.
c
SG1 had surgery 6 weeks after the completion of CRT (standard of care); SG2 had surgery 11 weeks after the completion of CRT, and had 2 cycles of modified FOLFOX-6 during the waiting period.