Fig. 8.

CMR of gadolinium-labeled macrophages in the mouse heart after MI. (A) A relaxivity (R1) map calculated from a Look-Locker image series demonstrates enhanced R1 in the infarct zone (white arrows), indicating the presence of labeled macrophages. (B) A map of end-systolic Ecc acquired using cine DENSE in the same location delineates the infarcted region as a region of diminished contractile function. Together, these images demonstrate that macrophage infiltration is confined to the infarcted region, with greatest intensity in the core of the infarct. Figure components reprinted with permission from [94] Naresh et al. Circulation. 2010; 122: A17344