Figure 3.
Figure 3A Enriched pathways recruited by lithium network nodes. Bars are colored to indicate those pathways containing or lacking one or a combination of AKT1/2, MAPK1/3 and GSK3B. Red bars represent pathways that contain AKT1/2, MAPK1/3 and GSK3B; purple bars include AKT1/2 and MAPK1/3; yellow bars contain AKT1/2; green bars contain GSK3B; AKT1/2, MAPK1/3 and GSK3B are absent in pathways represented by black bars and blue bars contain MAPK1/3; sky blue bars contain both GSK3B and MAPK1/3. Abbreviations: AJ=adherens junction; BCR=B cell receptor signaling; ECSHPI=epithelial cell signaling in Helicobacter pylori infection; FA=focal adhesion; FceRI=Fc epsilon RI signaling; FcgRMP=Fc gamma R-mediated phagocytosis; GJ=gap junction; LTD=long term depression; LTM=leukocyte transendothelial migration; LTP=long term potentiation; NKCMC=natural killer cell mediated cytotoxicity; NOD-like R=NOD-like receptor; OM=oocyte meiosis; P-MOM=progesterone mediate oocyte maturation; TCR=T cell receptor signaling; Toll-like R=Toll-like receptor signaling. Lists of nodes populating individual pathways are available upon request.
Figure 3B Enriched pathways recruited by valproate network nodes. Representations are as in Figure 3A.
Figure 3C Enriched pathways recruited by lithium-valproate intersecting network nodes. Representations are as in Figure 3A.