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. Author manuscript; available in PMC: 2012 Jul 19.
Published in final edited form as: Biochemistry. 2011 Jun 24;50(28):6196–6207. doi: 10.1021/bi2004284

Table 2.

Average values of overall order parameters (S2), and deviations from the average overall S2 for the Switch I and II regions for Cdc42 wild type, and Cdc42(T35A). Both proteins were in the GDP-bound form. Residue ranges of each region is given in the parentheses.

Cdc42(WT) Cdc42(T35A)
Average S2 protein 0.89 ± 0.04 0.89 ± 0.04
Average Switch I S2(28–41) 0.73 ± 0.10 0.81 ± 0.03
Average Switch II S2(57–74) 0.85 ± 0.091 0.88 ± 0.05
%ΔS2 (Switch I) 18.5% 8.6%
%ΔS2 (Switch II) 4.6% 1.5%

Where %ΔS2 = |(avgS2protein – avgS2region)/avgS2protein|×100.