Table III.

Suggested Apparatus for Drug Release Testing of Various Dosage Forms

Dosage form example	Release method
Oral solid dosage forms (conventional)	Basket apparatus, paddle apparatus, reciprocating cylinder or flow-through cell
Oral suspensions	Paddle apparatus
Oral disintegrating tablets	Paddle apparatus and disintegration method
Chewable tablets	Basket apparatus, paddle apparatus or Reciprocating cylinder
Powders and granules	Flow-through cell (powder/granule sample cell)
Thin dissolvable films	Basket apparatus and disintegration method
Chewing gum	Special apparatus (Ph. Eur.)
Dermal delivery systems (patches)	Paddle over disk
Topical (semisolid dosage forms)	Franz cell diffusion system
Suppositories	Paddle apparatus, modified basket apparatus or dual chamber flow-through cell
Microparticulate formulations	Modified flow-through cell
Implants	Modified flow-through cell
Aerosols	Cascade impactor