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. 2011 Apr 14;12(2):514–520. doi: 10.1208/s12249-011-9609-y

Table II.

Permeation Parameters: Flux (J), Lag Time and Percent Sunscreen Permeated at the End of the Experiment (Q%24 h) from Different Formulations Containing the Compound Alone (FA) or its α-Cyclodextrin Complex (CD/FA)

Formulations J (μg/cm2.h) Lag time (h) Q%24 h
O/W-FA 8.48 ± 2.31 8.79 ± 1.09 1.04 ± 0.20
O/W-CD/FA 4.76 ± 0.83 8.36 ± 0.38 0.51 ± 0.06*
Gel A-FA 8.38 ± 0.89 2.64 ± 0.07 1.47 ± 0.15
Gel A-CD/FA 1.56 ± 0.62* 7.87 ± 1.98* 0.18 ± 0.07*
Gel B-FA 5.72 ± 0.50 10.32 ± 0.51 0.65 ± 0.07
Gel B-CD/FA 0.54 ± 0.10* 9.10 ± 0.15 0.07 ± 0.01*

*Significantly different from the corresponding FA formulation, p < 0.05