Table 2.
The DDD and PDD:DDD ratios of the different substances
| Drug class (ATC code) | DDD (mg) | Percentage of patients | PDD:DDD ratio | |
|---|---|---|---|---|
| Mean | Median; IQR | |||
| Beta-blockers (C07AB) | 100 | 0.84 | ||
| Bisoprolol | 10 | 52 | 0.75 | 0.56; 0.55–1.09 |
| Metoprolol | 150 | 33 | 0.85 | 0.73; 0.52–1.15 |
| Nebivolol | 5 | 7 | 1.15 | 1.10; 1.09–1.11 |
| Talinolol | 100 | 4 | 1.15 | 1.10; 0.86–1.37 |
| Atenolol | 75 | 2 | 0.84 | 0.73; 0.37–1.15 |
| Other drugs, each with <2% | 2 | 1.05–1.23 | ||
| Thiazide diuretics (C03AA) | 100 | 1.00 | ||
| Hydrochlorothiazide | 25 | 100 | 1.00 | 1.09; 0.73–1.10 |
| Dihydropyridine calcium channel blockers (C08CA) | 100 | 1.51 | ||
| Amlodipine | 5 | 37 | 1.69 | 1.64; 1.10–2.19 |
| Nitrendipine | 20 | 22 | 1.27 | 1.10; 1.00–1.72 |
| Lercanidipine | 10 | 16 | 1.75 | 1.83; 1.10–2.19 |
| Nifedipine | 30 | 12 | 1.03 | 0.99; 0.67–1.36 |
| Felodipine | 5 | 9 | 1.58 | 1.17; 1.10–2.19 |
| Other drugs, each with <2% | 4 | 0.44–1.65 | ||
| Angiotensin-II receptor blockers (C09CA) | 100 | 1.88 | ||
| Candesartan | 8 | 26 | 2.50 | 2.15; 1.67–3.28 |
| Valsartan | 80 | 21 | 1.91 | 2.13; 1.22–2.15 |
| Olmesartan medoxomil | 20 | 20 | 1.36 | 1.08; 1.07–2.13 |
| Telmisartan | 40 | 11 | 1.88 | 2.14; 1.09–2.15 |
| Irbesartan | 150 | 11 | 1.76 | 2.13; 1.08–2.15 |
| Losartan | 50 | 7 | 1.45 | 1.09; 1.07–2.00 |
| Eprosartan | 600 | 3 | 1.10 | 1.08; 1.07–1.08 |
| ACE inhibitors (C09AA) | 100 | 2.17 | ||
| Ramipril | 2.5 | 34 | 3.29 | 3.13; 2.17–4.38 |
| Enalapril | 10 | 33 | 1.70 | 1.47; 1.02–2.20 |
| Lisinopril | 10 | 14 | 1.64 | 1.41; 1.09–2.19 |
| Captopril | 50 | 9 | 1.38 | 1.10; 0.56–1.97 |
| Quinapril | 15 | 5 | 1.20 | 1.10; 0.72–1.47 |
| Other drugs, each with <2% | 5 | 0.93–2.02 | ||
IQR = interquartile range (50% of the values lie between the lower and upper limits)
Data in bold are drug classes. The rest are substances