Table 4.
Prescribed DDD per patient per day for antihypertensive drug classes used as monotherapy in patients with a drug change
| Initial druga | ||||||
|---|---|---|---|---|---|---|
| Subsequent drug | C07AB (mean) | C03AA (mean) | C08CA (mean) | C09CA (mean) | C09AA (mean) | Patients (n) |
| C07AB (Beta-blockers) | – | 1.01 | 1.48 | 1.83 | 2.06 | 1802 |
| – | 0.85 | 0.84 | 0.81 | 0.75 | 1614 | |
| C03AA (Thiazide diuretics) | 0.84 | – | 1.65 | 2.19 | 2.17 | 200 |
| 0.91 | – | 0.97 | 0.98 | 0.96 | 238 | |
| C08CA (Calcium channel blockers) | 0.90 | 1.08 | – | 2.14 | 2.40 | 1099 |
| 1.52 | 1.70 | – | 1.52 | 1.52 | 1048 | |
| C09CA (Angiotensin-II receptor blockers) | 0.83 | 0.98 | 1.54 | – | 2.38 | 473 |
| 1.90 | 1.84 | 2.01 | – | 1.83 | 569 | |
| C09AA (ACE inhibitors) | 0.79 | 1.09 | 1.43 | 1.69 | – | 1418 |
| 2.17 | 2.53 | 2.3 | 2.59 | – | 1523 | |
aThe pairs of figures in the table represent, above, the DDD of the initial drug (i.e. the drug before drug change) and, below,
the DDD of the subsequent drug (i.e. the prescribed drug after drug change)