Fig. 1.

The performance of Abcg5−/− compared to Abcg5+/+ mice in the ORT. The Abcg5 genotype had no influence on object memory performance in an ORT with a 1 h delay between Tr1 and Tr2. Animals that did not reach the minimum of 5 s exploration in ORT in either Tr1 or Tr2 were excluded from d2 analysis (exclusion numbers: Abcg5−/− (n = 1) and Abcg5+/+ (n = 1)) (Sik et al. 2003). Extreme values were excluded by means of Dixon’s principles of exclusion of extreme values (exclusion numbers: Abcg5−/− (n = 0) and Abcg5+/+ (n = 1; d2 = 0.60)). No differences in d2 values could be detected between Abcg5−/− (n = 7) and Abcg5+/+ (n = 7) (a). T1(s) and T2(s) exploration times in respectively Tr1 and Tr2 were not different between Abcg5−/− (n = 8) and Abcg5+/+ (n = 9) (data not shown). Values are displayed as mean +/− SEM