Table 5.
Reproducibility and repeatability | |||||
---|---|---|---|---|---|
Criteria set for positive control/CV%/p–value | Obtained positive control value | ||||
Technician 1 –microscopic analyst 1 mean (n = 24) | Technician 1 – microscopic analyst 2 mean (n = 24) | Technician 2 –microscopic analyst 1 mean (n = 24) | Technician 2 –microscopic analyst 2 mean (n = 24) | ||
Day 1 (n = 48) | ≥5.75 | 5.79 | 5.833 | 5.75 | 5.75 |
Day 2 (n = 48) | ≥5.75 | 5.833 | 5.833 | 6.583 | 6.083 |
Day 3 (n = 48) | ≥5.75 | 5.875 | 5.75 | 6.625 | 6.5 |
Mean between days | ≥5.75 | 5.833 | 5.805 | 6.319 | 6.111 |
Day to day variation among technicians (CV%) | ≤15% | 0.59% | 0.67% | 6.38% | 5.02% |
Day to day variation among technicians (one-way ANOVA) | p < 0.05 | ns, p = 0.906 | ns, p = 0.064 | ||
Day to day variation between analysts (CV%) | ≤15% | 0.34% | %2.37 | ||
Person to person variation between technicians | 5.63% | 0.64% | |||
Person to person variation between technicians (statistical significance, unpaired t-test) | p < 0.05 | p = 0.007 | |||
Person to person variation between analysts (statistical significance, paired t-test) | p < 0.05 | ns, p = 0.2084 | |||
Total mean of positive control | ≥5.75 | 6.017 | |||
Total variation of positive control (CV%) | ≤15% | 1.39% |
CV, coefficient of variation, ns, non-significant.