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. Author manuscript; available in PMC: 2011 Jul 13.
Published in final edited form as: Clin Cancer Res. 2008 Jun 15;14(12):4016–4024. doi: 10.1158/1078-0432.CCR-08-0106

Figure 2. Example of mutations in 2 ACC and 1 ACA.

Figure 2

A and B, missense mutations in 2 ACC (R804H and A349) and 1 ACA (M878V) in leukocyte DNA (heterozygous state) and in the corresponding tumor (hemizygous state). In the tumor sample, the wild-type allele is lost and only the mutated allele is present. C, wild-type sequence.