Skip to main content
. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: J Immunol. 2011 May 25;187(1):337–349. doi: 10.4049/jimmunol.1003525

Figure 7. Cd101 alleles regulate the resistance and susceptibility to liver disease induced by N. aro-infection.

Figure 7

Expression of the NOD Cd101 allele induces a more tolerogenic milieu in the liver by promoting Treg responses whereas expression of the B6 Cd101 allele triggers an overzealous T cell response upon infection with N. aro. The loss of CD101 expression on DCs drives the enhanced IFN-γ and IL-17 production by T cells and subsequently the induction of liver disease upon N. aro-infection.