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. Author manuscript; available in PMC: 2012 Jun 10.
Published in final edited form as: Circ Res. 2011 Apr 21;108(12):e15–e26. doi: 10.1161/CIRCRESAHA.110.235531

Figure 3. Sox9 rescues PDGF receptor mutant phenotypes.

Figure 3

(A) qPCR for Sox9 expression in primary epicardial cultures stimulated with PDGFBB for 24h. (*) p<0.001 (B) βcatenin and phalloidin localization of control and PDGFREKO cultures stimulated with hTGFβ1 and PDGFBB in the presence of adenoviral LacZ or Sox9. (C–E) qPCR analysis of epithelial, mesenchymal, and EMT transcription factors of primary epicardial cultures transduced with adenoviral Sox9. Data were compared to vehicle treated, GFP adenoviral transduced control epicardial cultures (Online Figure III, D–F) (represented as a baseline of 1.0). Data are represented as mean ± SD. N values are indicated in parentheses. (*) p<0.001 (n.s. – no significant difference)