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. Author manuscript; available in PMC: 2012 Jun 10.
Published in final edited form as: Circ Res. 2011 Apr 21;108(12):e15–e26. doi: 10.1161/CIRCRESAHA.110.235531

Figure 6. PDGFRα is required for epicardial derived cardiac fibroblast formation.

Figure 6

(A) Percentage of epicardially-derived cardiac fibroblasts (Gata5creTg; R26RYFP) from P21–P28 PDGF receptor mutant hearts. There was a subpopulation of Thy1+ CD31+42, 43 cells that were excluded from our analysis. (B) β-galactosidase activity (blue) in passage 1 primary cardiac fibroblast cultures using P21–P28 Gata5creTg; R26RLacZ hearts to follow EPDCs. Nuclear fast red was used as a counterstain. (C) Quantification of blue cells in (B). Data are represented as mean ± SD. N values are indicated in parentheses. (*) p<0.001 (compared to control)