Table 1.
Cutting edge topics of the current controversy on BPA
Are the studies used for regulatory purposes flawed? |
Do oral low doses below 5 mg/kg bw/day cause adverse health effects in laboratory animals? |
How can differences between industry sponsored and publicly sponsored studies be explained? |
Swallow or inject? What is the relevance of the oral route versus implantation of pumps or intravenous injection? |
Can rodents be used to extrapolate to the human situation? |
To which degree are embryos, babies, or children more susceptible? |
How critical is exposure by intravenous infusion in intensive care units? |
How critical is tissue deconjugation of BPA-glucuronide and BPA-sulfate? |
How can biomonitoring support risk evaluation? |
What are the mechanisms of action of BPA? Does the multitude of mechanisms other than estrogen receptor activation make the substance more dangerous? |
Why are recent governmental responses inconsistent? |