Postoperative plasma ACTH and serum cortisol responses to CRH stimulation testing (1 μg/kg iv) 4–24 d after surgery at 0800 and/or 2000 h, according to long-term follow-up remission status (●, recurrence; ○, remission). Values are mean ± sem. (To convert ACTH to picomoles per liter, multiply by 0.22; to convert cortisol to nanomoles per liter, multiply by 27.6.)