Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Ceramide-metabolizing pathways. The de novo synthesis of ceramide begins with the conversion of dihydro-sphingosine into dihydro-ceramide by ceramide synthase and then further converted into ceramide. ASMase and NSMase catalyze the hydrolysis of phosphodiester bond in SM and produces ceramide and choline phosphate. Ceramide is converted back into SM by SM synthase and degraded by ceramidase.
