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Circulating FIX antigen levels and anti-hFIX IgG titers in rabbits injected with AAV-5 vectors. Rabbits were injected via the peripheral vein with AAV-5 at 1 × 1013 vg/kg (high-dose, A and B) or 1 × 1012 vg/kg (low-dose, C and D). Data are shown for each individual animal. Color images available online at www.liebertonline.com/hum.
