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. 2010 Nov 22;22(7):829–841. doi: 10.1089/hum.2010.162

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Copyright 2011, Mary Ann Liebert, Inc.

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FIG. 2. — Follow-up of transduced donor T cells: (A) UPN 914; (B) UPN 919; (C) UPN 1021; (D) UPN 1040; (E) UPN 1048; (F) UPN 1108; (G) UPN 1159; (H) UPN 1190; (I) UPN 1208. Shown is the percentage of donor chimerism in peripheral blood (solid squares; left y axis) and the percentage of ΔLNGFR-expressing cells (FACS) (triangles; right y axis) plotted against days after HSCT. The time of transfusion of donor lymphocytes is indicated by an arrow (DLI SFCMM-3). UPN 914 received more than one DLI, but only the first one was transduced; all other patients have received only one DLI to date (DLI SFCMM-3). UPN 919 (B) and UPN 1108 (F) received only 4 × 10⁶ SFCMM-3-transduced cells/kg (Table 2). HSCT, hematopoietic stem cell transplantation; LNGFR, low-affinity nerve growth factor receptor.